Rheumatoid Arthritis: Early Diagnosis and TreatmentProfessional Communications, 2010 - 367 pages Emphasizes the importance of early intervention in RA with focus on pharmacologic treatments of RA. Detailed information on the various medications employed in treatment, including corticosteroids, NSAIDs, DMARDs, biologic agents, and combination therapy, is reviewed, including evidence-based data on efficacy, safety, side effects, and monitoring requirements. Clinical evaluation is presented, including lab findings, joint scoring, diagnostic criteria, and radiographic outcomes. Surgical options and the management of advanced RA are discussed. |
Expressions et termes fréquents
abatacept ACR20 response active RA adalimumab adverse events agents aggressive anakinra Ann Rheum anti-TNF arthritis patients Arthritis Rheum assessed biologic cells certolizumab pegol chronic clinical trials combination DMARD combination therapy compared corticosteroids cyclosporine cytokines diagnosis disability disease activity disease duration DMARD DMARD therapy dose double-blind drug early RA patients early rheumatoid arthritis effective efficacy erosions etanercept Figure function golimumab hepatic increased inflammation infliximab inhibition initial joint count leflunomide lymphoma methotrexate mg/day mg/kg monoclonal antibody monotherapy necrosis factor new-onset NSAIDs onset pain patient-years patients receiving patients treated patients with active patients with early patients with RA patients with rheumatoid placebo placebo-controlled polyarthritis prednisone psoriatic arthritis radiographic radiographic progression randomized receptor referral remission rheumatoid arthritis rheumatoid nodules Rheumatol rheumatologists risk rituximab rofecoxib safety serious infections serum significantly swollen joints symptoms synovial T-cell TNF inhibitors tocilizumab toxicity treatment week 24